Dermal Fillers

Combining the advantages of collagen and hyaluronic acid for skin regeneration

Skin rejuvenation procedures are increasing in popularity, especially nonsurgical treatments such as dermal filler injections. Hyaluronic acid is water-retaining molecule widely used for dermal filling, but on its own, lacks the ability to promote cell proliferation and tissue regeneration. This results in a limited-lasting effect.

The combination of hyaluronic acid with a photocurable version of CollPlant’s tissue regenerating rhCollagen, serves as the basis for a new dermal filler product line now in development. We are developing a photocurable regenerative filler comprised of rhCollagen and hyaluronic acid which is intended to provide several revolutionary effects: lifting, sculpturing ability, retention to the host tissue, and tissue regeneration.

The photocurable regenerative filler is intended for injection in a semiliquid phase and hardened in-situ post injection by light illumination through the skin. Utilization of photocuring technology is expected to ease the injection process, particularly in subcutaneous and supraperiosteal applications.

As the hyaluronic acid and rhCollagen degrade, a newly formed tissue is expected to regenerate and take their place.

The photocurable dermal filler is under development and is not commercially available.

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