Collink.3D is the first and only plant-based human collagen bioink platform, mass produced at high consistency, enabling perfect mimicry of the native properties of tissues and organs.
Collink.3D 50L is based on recombinant human type I collagen (rhCollagen), that was chemically modified to generate a curable bioink in a dry form, with approximately 50% of the primary amines converted into methacrylamides.
|Appearance: Color||White to Off White|
|Appearance: Form||Dry cake|
|Identity||Type I collagen|
|Purity||95% Type I collagen|
|Degree of Functionalization||45-65%|
|Dry weight||100-120 mg|
|pH after reconstitution#||1.9 – 2.4|
|Color after reconstitution#||Clear, transparent, no visible particles|
|Total Aerobic Microbial Counts||< 10 CFU/ml|
|Total Yeast and Mold Counts||< 10 CFU/ml|
|Endotoxins||< 7 EU/ml|
|Elemental analysis||According to USP<233>|
|Curing Kinetics- Time to G’ >100 Pa||≤ 5 sec|
#For Collink3D 50L 10 mg/mL solution in 10 mM HCl after 3 hours
Recombinant human collagen extracted from genetically-engineered plants, without any animal-derived substances or reagents.
• Animal free
• Optimal rheology at room temperature
• Supports high viability of different cell types
• Biocompatible, non-immunogenic
Collink.3DTM enables fabrication of 3D constructs with complex architectures, meeting the demand for specific geometric, physical and biological properties. Biofabricated constructs made with Collink.3DTM can be used in a wide range of soft and hard tissue applications, including tissue models for drug discovery and screening, as well as the development and manufacture of tissue and organ transplants.
Owing to its cytocompatibility, Collink.3DTM supports significant high viability of various cell types – fibroblasts, stem cells, induced pluripotent stem cells, endothelial and epithelial cells.
Extensive studies carried out to characterize the chemical, physical and biological characteristics of Collink.3DTM confirmed its identity to human type I collagen and its performance as a bioink.
Collink3D™: Ready, set, print!
For more information, contact us at Collink.3D@collplant.com